Compact tunable Cr:LiSAF laser for infrared matrix-assisted laser desorption/ionization.

Continuous Flow Atmospheric Pressure Laser Desorption/Ionization Using a 6–7-µm-Band Mid-Infrared Tunable Laser for Biomolecular Mass Spectrometry

A continuous flow atmospheric pressure laser desorption/ionization technique using a porous stainless steel probe and a 6-7-µm-band mid-infrared tunable laser was developed. This ion source is capable of direct ionization from a continuous flow with a high temporal stability. The 6-7-µm wavelength region corresponds to the characteristic absorption bands of various molecular vibration modes, in...

Fundamentals of matrix-assisted laser desorption/ionization mass spectrometry with pulsed infrared lasers

The fundamental work and current knowledge on the mechanisms of matrix-assisted laser desorption ionization with pulsed infrared lasers is reviewed and discussed, with a special emphasis on the work performed in the laboratory of the authors in the recent past. The role of the different relevant irradiation parameters (laser wavelength, laser pulse duration, irradiated area and laser fluence) a...

Using tunable diode laser spectroscopy to detect trace moisture in ammonia

Detection of moisture contamination in hydride gases, such as ammonia used for epitaxial growth, has become a significant concern for manufacturers of III-V compound semiconductors. The presence of moisture in NH3 can negatively affect device properties, such as minority-carrier lifetimes and luminescent efficiency in light-emitting diodes. Tunable diode laser spectroscopy (TDLAS) has emerged a...

Gas sensing in industry by tunable diode laser spectroscopy (TDLS)

Resolution of infrared matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using glycerol; enhancement with a disperse laser beam.

Some experimental factors affecting the resolution in glycerol infrared matrix-assisted laser desorption/ionization (IR-MALDI) time-of-flight (TOF) mass spectrometry were investigated. Loading the sample inside a cavity covered with a grid was found to improve the resolving power as reported previously, although not to the extent attainable in UV-MALDI using the same instrument. The resolving p...